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Age-associated Metastatic Potential of Melanoma in Lymph Nodes: A Preliminary Gene Association Study.

Journal of the European Academy of Dermatology and Venereology JEADV(2024)

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Journal of the European Academy of Dermatology and VenereologyEarly View LETTER TO THE EDITOR Age-associated metastatic potential of melanoma in lymph nodes: A preliminary gene association study C. C. Zouboulis, Corresponding Author C. C. Zouboulis [email protected] orcid.org/0000-0003-1646-2608 Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg, Dessau, Germany Correspondence C. C. Zouboulis, Departments of Dermatology, Venereology, Allergology and Immunology, Staedtisches Klinikum Dessau, Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg, Auenweg 38, 06847 Dessau, Germany. Email: [email protected]Search for more papers by this authorA. J. Dixon, A. J. Dixon orcid.org/0000-0001-8071-7199 Australasian College of Cutaneous Oncology, Melbourne, Victoria, AustraliaSearch for more papers by this authorH. K. Steinman, H. K. Steinman Campbell University, Buies Creek, North Carolina, USASearch for more papers by this authorM. Sladden, M. Sladden University of Tasmania, Launceston, Tasmania, AustraliaSearch for more papers by this authorA. Kyrgidis, A. Kyrgidis orcid.org/0000-0003-3896-0309 Aristotle University of Thessaloniki, Thessaloniki, GreeceSearch for more papers by this author C. C. Zouboulis, Corresponding Author C. C. Zouboulis [email protected] orcid.org/0000-0003-1646-2608 Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg, Dessau, Germany Correspondence C. C. Zouboulis, Departments of Dermatology, Venereology, Allergology and Immunology, Staedtisches Klinikum Dessau, Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg, Auenweg 38, 06847 Dessau, Germany. Email: [email protected]Search for more papers by this authorA. J. Dixon, A. J. Dixon orcid.org/0000-0001-8071-7199 Australasian College of Cutaneous Oncology, Melbourne, Victoria, AustraliaSearch for more papers by this authorH. K. Steinman, H. K. Steinman Campbell University, Buies Creek, North Carolina, USASearch for more papers by this authorM. Sladden, M. Sladden University of Tasmania, Launceston, Tasmania, AustraliaSearch for more papers by this authorA. Kyrgidis, A. Kyrgidis orcid.org/0000-0003-3896-0309 Aristotle University of Thessaloniki, Thessaloniki, GreeceSearch for more papers by this author First published: 13 February 2024 https://doi.org/10.1111/jdv.19850Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Open Research DATA AVAILABILITY STATEMENT The data that support the findings of this study are available from the corresponding author upon reasonable request. Data sets related to this article are hosted at the Gene Expression Omnibus (https://www.ncbi.nlm.nih.gov/geo/) data repositories GSE8401 and GSE43081. REFERENCES 1Ribero S, Stucci LS, Marra E, Marconcini R, Spagnolo F, Orgiano L, et al. Effect of age on melanoma risk, prognosis and treatment response. Acta Derm Venereol. 2018; 98: 624–629. 10.2340/00015555-2944 CASPubMedWeb of Science®Google Scholar 2Menefee DS, McMasters A, Pan J, Li X, Xiao D, Waigel S, et al. Age-related transcriptome changes in melanoma patients with tumor-positive sentinel lymph nodes. Aging. 2020; 12: 24–24939. 10.18632/aging.202435 Google Scholar 3Makrantonaki E, Brink TC, Zampeli V, Elewa RM, Mlody B, Hossini AM, et al. Identification of biomarkers of human skin ageing in both genders: Wnt signalling – a label of skin ageing? PLoS One. 2012; 7:e50393. 10.1371/journal.pone.0050393 CASPubMedWeb of Science®Google Scholar 4Mulder EEAP, Dwarkasing JT, Tempel D, van der Spek A, Bosman L, Verver D, et al. 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