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Point Estimation, Confidence Intervals, and P-values for Optimal Adaptive Two-Stage Designs with Normal Endpoints

Jan Meis,Maximilian Pilz,Bjoern Bokelmann,Carolin Herrmann,Geraldine Rauch,Meinhard Kieser

STATISTICS IN MEDICINE（2024）

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Key words
bias,confidence intervals,optimal adaptive designs,P-values,point estimation
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