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Cancer Precision-Prevention Trial of Metformin in Adults with Li Fraumeni Syndrome (MILI) Undergoing Yearly MRI Surveillance: a Randomised Controlled Trial Protocol

Miriam Dixon-Zegeye,Rachel Shaw,Linda Collins, Kendra Perez-Smith,Alexander Ooms, Maggie Qiao,Pan Pantziarka,Louise Izatt,Marc Tischkowitz,Rachel E. Harrison,Angela George,Emma R. Woodward,Simon Lord,Lara Hawkes,D. Gareth Evans,James Franklin,Helen Hanson,Sarah P. Blagden

TRIALS（2024）

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关键词
Metformin,Li-Fraumeni syndrome,LFS,Cancer,p53,TP53,Precision-Prevention,Chemoprevention
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