Axicabtagene ciloleucel versus tisagenlecleucel for relapsed or refractory large B-cell lymphoma: a systematic review and meta-analysis

Transplantation and Cellular Therapy(2024)

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摘要
•Meta-analysis of real-world studies on axi-cel vs tisa-cel in rrDLBCL•Axi-cel was associated with significantly improved responses and progression-free survival•Tisa-cel was associated with significantly reduced higher grade CRS and neurotoxicity•Tisa-cel showed significantly reduced utilization of resources
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关键词
DLBCL,axicabtagene,tisagenlecleucel,CAR-T,CRS,ICANS
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