Efficient and Scalable Synthesis of 6,6-Dimethyl-3-oxabicyclo [3.1.0]Hexan-2-one Through Organocatalyzed Desymmetrization and Chemoselective Reduction

Guillaume Tintori,Clement Jacob, Christine Delsarte, Francois Potie, Laurence Grimaud,Maxime Vitale,Pierre-Georges Echeverria

SYNTHESIS-STUTTGART（2024）

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desymmetrization,organocatalysis,chemoselective carboxylic acid reduction,process development,kinetics,scale-up

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