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Linker Substitution Influences Succinimide Ring Hydrolysis Equilibrium Impacting the Stability of Attachment to Antibody-Drug Conjugates

Lu Wang,Adrian D. Hobson, Paulin L. Salomon,Julia Fitzgibbons,Jianwen Xu, Sean McCarthy, Kan Wu,Ying Jia,Axel Hernandez,Xiang Li, Zhou Xu,Zhongyuan Wang,Yajie Yu, Junxian Li, Lin Tao

RSC MEDICINAL CHEMISTRY（2024）

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Antibody Engineering
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