Identifying the Most At-Risk Age-Group and Longitudinal Trends of Drug Allergy Labeling Amongst 7.3 Million Individuals in Hong Kong

Incorrect drug ‘allergy’ labels remain a global public health concern. Identifying regional trends of drug allergy labeling can guide appropriate public health interventions, but longitudinal or population drug allergy studies remain scarce. We analysed the serial epidemiology of drug allergy labeling to identify specific subgroups at highest risk of drug allergy labeling for potential interventions. Longitudinal, population-wide drug allergy labels and clinical data from over 7,337,778 individuals in Hong Kong between 2016 and 2021 were analysed. The absolute prevalence and incidence of documented drug allergy were 5.61