Single-center retrospective observational study on predictors of residual mitral regurgitation 1 year after MitraClip implantation

Background.The extent of residual mitral regurgitation (MR) (1+ vs >= 2+) has a notable impact on the outcome of MitraClip (MC) repair of significant functional MR. In this retrospective single-center study, we evaluated the predictors of MI >= 2+ at 1 year in one of our case series. Methods.Overall, 58 patients with moderate severe functional MR underwent MC implantation; of these, 48 patients had instrumental clinical follow-up for 1 year. Results.At 1 year, 10 patients died (mortality 17.2%). In the remaining 48 patients, the incidence of rehospitalization was 8.3%, and the incidence of MR grade 1+ and >= 2+ was 54.1% (n = 26) and 45.9% (n = 22), respectively. In patients with MR >= 2+, clinical and instrumental outcomes were worse than in patients with MR 1+. The height of the posterior leaflet and the extent of immediate postprocedural MR were independent predictors of MR >= 2+. Conclusions.Percutaneous repair with MC of moderate/severe functional MR has favorable 1-year out-comes in terms of mortality and rehospitalizations. The best results are achieved in patients with residual MR 1+. Echocardiographic parameters are independent predictors of residual MR >= 2+