Abstract 404: Gremlin1-Induced Endothelial Cell Proliferation is Mediated Via Antagonism of Bone Morphogenetic Protein Receptor 2-Induced Repression of CXCL12

Evan DeVallance,Daniel de Jesús,Sanghamitra Sahoo,Patrick J. Pagano

Arteriosclerosis, thrombosis, and vascular biology（2019）

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摘要

Pulmonary arterial hypertension (PAH) is a devastating disease with 7-year survival under 50%. A common feature of PAH is vascular remodeling mediated by altered bone morphogenetic protein receptor...

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