Abstract 19303: A Small Molecular Activator of the ER Proteostasis Regulator, ATF6, is Beneficial in the Ischemic Heart

Erik A. Blackwood,Khalid Azizi,Jung-Kang Jin,Lars Plate,Ryan J Paxman,Donna J. Thuerauf,Luke Wiseman,J.W. Kelly, C

Circulation（2017）

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摘要

Rationale: Reactive oxygen species generated during myocardial ischemia/reperfusion (I/R) potentiate myocyte death and cardiac dysfunction. Recently, we found a new, previously unappreciated role f...

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