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PIK3CA Mutation Status in Apocrine Carcinoma Arising in Apocrine Gland Hyperplasia/apocrine Nevus: A Study of Four Cases.

Journal of cutaneous pathology(2024)

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Abstract
Journal of Cutaneous PathologyEarly View BRIEF COMMUNICATION PIK3CA mutation status in apocrine carcinoma arising in apocrine gland hyperplasia/apocrine nevus: A study of four cases Keisuke Goto MD, Corresponding Author Keisuke Goto MD [email protected] orcid.org/0000-0002-4165-1809 Department of Diagnostic Pathology, Shizuoka Cancer Center Hospital, Sunto, Japan Department of Pathology, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital, Tokyo, Japan Department of Diagnostic Pathology and Cytology, Osaka International Cancer Institute, Osaka, Japan Department of Dermato-Oncology/Dermatology, National Hospital Organization Kagoshima Medical Center, Kagoshima, Japan Department of Pathology, Itabashi Central Clinical Laboratory, Tokyo, Japan Department of Anatomic Pathology, Tokyo Medical University, Tokyo, Japan Department of Diagnostic Pathology, Chutoen General Medical Center, Kakegawa, Japan Department of Clinical Laboratory and Diagnostic Pathology, Osaka National Hospital, Osaka, Japan Department of Dermatology, Hyogo Cancer Center, Akashi, Japan Correspondence Keisuke Goto, Department of Diagnostic Pathology, Shizuoka Cancer Center Hospital, 1007 Shimonagakubo, Nagaizumi, Sunto, Shizuoka 411-8777, Japan. Email: [email protected]Search for more papers by this authorYukiko Kiniwa MD, PhD, Yukiko Kiniwa MD, PhD orcid.org/0000-0003-3757-7375 Department of Dermatology, Shinshu University School of Medicine, Matsumoto, JapanSearch for more papers by this authorTsunekazu Hishima MD, PhD, Tsunekazu Hishima MD, PhD Department of Pathology, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital, Tokyo, JapanSearch for more papers by this authorKeiichiro Honma MD, PhD, Keiichiro Honma MD, PhD orcid.org/0000-0001-5193-5891 Department of Diagnostic Pathology and Cytology, Osaka International Cancer Institute, Osaka, JapanSearch for more papers by this authorShigeto Matsushita MD, PhD, Shigeto Matsushita MD, PhD orcid.org/0000-0003-2001-5341 Department of Dermato-Oncology/Dermatology, National Hospital Organization Kagoshima Medical Center, Kagoshima, JapanSearch for more papers by this authorMegumi Aoki MD, Megumi Aoki MD Department of Dermato-Oncology/Dermatology, National Hospital Organization Kagoshima Medical Center, Kagoshima, JapanSearch for more papers by this authorKatsuhiko Nishihara MD, Katsuhiko Nishihara MD orcid.org/0000-0002-3801-4278 Department of Dermato-Oncology/Dermatology, National Hospital Organization Kagoshima Medical Center, Kagoshima, JapanSearch for more papers by this authorTsubasa Hiraki MD, PhD, Tsubasa Hiraki MD, PhD Department of Diagnostic Pathology, Shizuoka Cancer Center Hospital, Sunto, JapanSearch for more papers by this author Keisuke Goto MD, Corresponding Author Keisuke Goto MD [email protected] orcid.org/0000-0002-4165-1809 Department of Diagnostic Pathology, Shizuoka Cancer Center Hospital, Sunto, Japan Department of Pathology, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital, Tokyo, Japan Department of Diagnostic Pathology and Cytology, Osaka International Cancer Institute, Osaka, Japan Department of Dermato-Oncology/Dermatology, National Hospital Organization Kagoshima Medical Center, Kagoshima, Japan Department of Pathology, Itabashi Central Clinical Laboratory, Tokyo, Japan Department of Anatomic Pathology, Tokyo Medical University, Tokyo, Japan Department of Diagnostic Pathology, Chutoen General Medical Center, Kakegawa, Japan Department of Clinical Laboratory and Diagnostic Pathology, Osaka National Hospital, Osaka, Japan Department of Dermatology, Hyogo Cancer Center, Akashi, Japan Correspondence Keisuke Goto, Department of Diagnostic Pathology, Shizuoka Cancer Center Hospital, 1007 Shimonagakubo, Nagaizumi, Sunto, Shizuoka 411-8777, Japan. Email: [email protected]Search for more papers by this authorYukiko Kiniwa MD, PhD, Yukiko Kiniwa MD, PhD orcid.org/0000-0003-3757-7375 Department of Dermatology, Shinshu University School of Medicine, Matsumoto, JapanSearch for more papers by this authorTsunekazu Hishima MD, PhD, Tsunekazu Hishima MD, PhD Department of Pathology, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital, Tokyo, JapanSearch for more papers by this authorKeiichiro Honma MD, PhD, Keiichiro Honma MD, PhD orcid.org/0000-0001-5193-5891 Department of Diagnostic Pathology and Cytology, Osaka International Cancer Institute, Osaka, JapanSearch for more papers by this authorShigeto Matsushita MD, PhD, Shigeto Matsushita MD, PhD orcid.org/0000-0003-2001-5341 Department of Dermato-Oncology/Dermatology, National Hospital Organization Kagoshima Medical Center, Kagoshima, JapanSearch for more papers by this authorMegumi Aoki MD, Megumi Aoki MD Department of Dermato-Oncology/Dermatology, National Hospital Organization Kagoshima Medical Center, Kagoshima, JapanSearch for more papers by this authorKatsuhiko Nishihara MD, Katsuhiko Nishihara MD orcid.org/0000-0002-3801-4278 Department of Dermato-Oncology/Dermatology, National Hospital Organization Kagoshima Medical Center, Kagoshima, JapanSearch for more papers by this authorTsubasa Hiraki MD, PhD, Tsubasa Hiraki MD, PhD Department of Diagnostic Pathology, Shizuoka Cancer Center Hospital, Sunto, JapanSearch for more papers by this author First published: 18 January 2024 https://doi.org/10.1111/cup.14588Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest. Open Research DATA AVAILABILITY STATEMENT The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions. REFERENCES 1Nishikawa Y, Tokusashi Y, Saito Y, Ogawa K, Miyokawa N, Katagiri M. A case of apocrine adenocarcinoma associated with hamartomatous apocrine gland hyperplasia of both axillae. Am J Surg Pathol. 1994; 18(8): 832-836. doi:10.1097/00000478-199408000-00010 10.1097/00000478-199408000-00010 CASPubMedWeb of Science®Google Scholar 2Kazakov DV, Michal M, Kacerovska D, McKee PH. Apocrine gland hyperplasia (apocrine nevus). In: DV Kazakov, M Michal, D Kacerovska, PH McKee, eds. Cutaneous Adnexal Tumors. Wolters Kluwer/Lippincott Williams & Wilkins; 2012: 155-157. 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Apocrine carcinoma with marked sebocyte-like cytological features: a report of two cases. J Cutan Pathol. 2023; 51: 92-98. doi:10.1111/cup.14539 10.1111/cup.14539 PubMedGoogle Scholar 7Dias-Santagata D, Lam Q, Bergethon K, et al. A potential role for targeted therapy in a subset of metastasizing adnexal carcinomas. Mod Pathol. 2011; 24(7): 974-982. doi:10.1038/modpathol.2011.48 10.1038/modpathol.2011.48 CASPubMedWeb of Science®Google Scholar 8Le LP, Dias-Santagata D, Pawlak AC, et al. Apocrine-eccrine carcinomas: molecular and immunohistochemical analyses. PloS One. 2012; 7(10):e47290. doi:10.1371/journal.pone.0047290 10.1371/journal.pone.0047290 CASPubMedWeb of Science®Google Scholar Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation
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