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Mrna-Laden Lipid-Nanoparticle-Enabled in Situ CAR-Macrophage Engineering for the Eradication of Multidrug-Resistant Bacteria in a Sepsis Mouse Model.

Chunwei Tang,Weiqiang Jing, Kun Han,Zhenmei Yang, Shengchang Zhang, Miaoyan Liu,Jing Zhang,Xiaotian Zhao,Ying Liu,Chongdeng Shi,Qihao Chai,Ziyang Li,Maosen Han,Yan Wang,Zhipeng Fu, Zuolin Zheng,Kun Zhao,Peng Sun,Danqing Zhu, Chen,Daizhou Zhang, Dawei Li,Shilei Ni,Tao Li,Jiwei Cui,Xinyi Jiang

ACS NANO（2024）

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关键词
sepsis,immunosuppression,methicillin-resistant Staphylococcus aureus,chimeric antigen receptormacrophage,lipid nanoparticle,in situ engineering
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