Do MYC rearrangements Matter in HIV-Associated Large B Cell Lymphomas? “EUROMYC” Study (a European retrospective study)

Chiara Pagani,Chiara Rusconi,Alessia Dalla Pria,Emanuele Ravano,Philipp Schommers,Mariana Bastos-Oreiro,Luisa Verga,Guido Gini,Michele Spina,Luca Arcaini,Sara Steffanoni,Davide Dalu,Lara Crucitti,Luisa Lorenzi,Piera Balzarini,Chiara Cattaneo, Lucia Bongiovanni,Andreas Rosenwald, Fabio Facchetti,Mark Bower

Blood advances（2024）

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摘要

-HIV-associated lymphomas with MYC rearrangement could be considered for an intensive therapeutic approach.-Standard (R)CHOP seems to give inferior complete remission rate and progression free survival in this subset of patients.

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关键词

HIV,large B-cell lymphoma,diffuse large B cell lymphoma,double-hit lymphoma,MYC,(R)CHOP,DA-EPOCH-R,intensive chemotherapy

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