Minocycline Mitigated Enduring Neurological Consequences in the Mice Model of Sepsis

Mahmoud Hosseini,Zahra Bardaghi,Hedyeh Askarpour, Mohammad Mahdi Jafari, Ahmad Golkar,Shima Shirzad,Arezoo Rajabian,Hossein Salmani

BEHAVIOURAL BRAIN RESEARCH（2024）

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摘要

•Minocycline reduced anxiety and depressive behaviors manifestation in septic mice.•Minocycline prevented prolonged oxidative stress injury in the post-septic brain.•Minocycline protected against sepsis-induced enduring cognitive impairment.

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Minocycline,Sepsis,Oxidative stress,Memory,Anxiety,Depression

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