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Post COVID-19 Condition among Adults in Malaysia Following the Omicron Wave: A Prospective Cohort Study.

PLoS ONE(2024)

Minist Hlth Malaysia

Cited 1|Views10
Abstract
Post COVID-19 condition is an important public health problem as we emerge from the COVID-19 pandemic. In this prospective cohort study, we aimed to determine the prevalence of this condition and assess its associated factors and impact on health-related quality of life in a population setting in Malaysia. Study was conducted from April to June 2022 when the Omicron variant predominated. All individuals testing positive for SARS-CoV-2 infection (RT-PCR, RTK-Ag) were invited for participation. Study questionnaires were delivered via the MySejahtera platform (mobile application). From the total of 44,386 participants who provided responses up to 3-months interval, 1,510 participants (3.4%) fulfilled the post COVID-19 condition criteria. Majority of the affected participants (83.8%, n = 1,265) experienced either cough, fatigue or forgetfulness-the three most common symptoms. Being females, having existing comorbidities, presence of symptoms and requiring hospital admission during the acute illness were associated with higher likelihoods of developing the post COVID-19 condition at 3-months interval. Amongst the 1,510 individuals, one in five had limitations in performing their usual daily activities while at least one in three expressed that their work was affected. Understanding this condition better is essential to guide strategic and responsive plans of action, which may require coordinated multidisciplinary interventions.
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要点】:本研究旨在确定马来西亚奥密克戎波次新冠后遗症的发生率,并评估其相关因素和对健康相关生活质量的影响,其创新点在于运用移动应用程序MySejahtera进行问卷调查,提高了参与度和数据收集的便捷性。

方法】:研究采用前瞻性队列研究设计,在2022年4月至6月间进行,当时奥密克戎变种占主导地位。所有SARS-CoV-2检测阳性(通过RT-PCR或RTK-Ag)的个体被邀请参与。研究问卷通过移动应用程序MySejahtera发放。

实验】:共有44,386名参与者完成了3个月内的调查,其中1,510名参与者(3.4%)符合新冠后遗症的标准。大多数受影响的参与者(83.8%,n=1,265)经历了咳嗽、疲劳或健忘,这三个是最常见的症状。在1,510人中,五分之一的人在执行通常的日常活动时有限制,而至少有三分之一的人表示他们的工作受到了影响。研究结果强调了新冠后遗症对患者生活质量的长期影响,为制定相应的公共卫生策略提供了科学依据。