Immunogenicity of a recombinant plant-produced respiratory syncytial virus F subunit vaccine in mice
Biotechnology Reports(2024)
摘要
•The RSV-F Fc fusion proteins, native construct and structural stabilized construct, were successfully produced in plant.•The plant produced RSV-F Fc fusion proteins were recognized by the monoclonal antibody Motavizumab specific against RSV-F protein.•The plant produced RSV-F Fc fusion proteins showed immunogenicity in mice.
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关键词
Subunit vaccine,Respiratory syncytial virus,plant-produced recombinant protein,Nicotianabenthamiana
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