A Pancreatic Cancer Organoid Platform Identifies an Inhibitor Specific to Mutant KRAS.

Xiaohua Duan,Tuo Zhang,Lingling Feng,Neranjan de Silva, Benjamin Greenspun, Xing Wang,Jenna Moyer,M. Laura Martin,Rohit Chandwani,Olivier Elemento,Steven D. Leach,Todd Evans,Shuibing Chen,Fong Cheng Pan

CELL STEM CELL（2024）

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KRAS,pancreatic organoid,SREBP2,cholesterol biosynthesis,perhexiline maleate,lung cancer organoids,colon cancer organoids,targeted therapy,orthotopic transplantation

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