Increased IGFBP proteolysis, IGF-I bioavailability and pappalysin levels in children with Prader-Willi syndrome.

Vicente Barrios,Álvaro Martín-Rivada,Gabriel Á Martos-Moreno,Sandra Canelles, Francisca Moreno-Macián, Carmen De Mingo-Alemany,Maurizio Delvecchio,Roberta Pajno,Danilo Fintini,Julie A Chowen,Jesús Argente

The Journal of clinical endocrinology and metabolism（2023）

引用 0|浏览4

暂无评分

摘要

The increase in PAPP-A could be involved in increased IGFBP proteolysis, promoting IGF-I bioavailability in children with PWS. Further studies are needed to establish the relationship between growth, GH resistance, and changes in the IGF axis during development and after GH treatment in these patients.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要