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Exploiting the Carboxylate-Binding Pocket of Β-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library

Suhyeorn Park,Jiayi Fan,Srinivas Chamakuri,Murugesan Palaniappan,Kiran Sharma,Xuan Qin,Jian Wang,Zhi Tan,Allison Judge,Liya Hu,Banumathi Sankaran,Feng Li,B. V. Venkataram Prasad,Martin M. Matzuk,Timothy Palzkill

JOURNAL OF MEDICINAL CHEMISTRY（2023）

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Beta-lactam Antibiotics
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