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Discovery of a 1,6-Naphthyridin-4-one-based AXL Inhibitor with Improved Pharmacokinetics and Enhanced in Vivo Antitumor Efficacy.

European journal of medicinal chemistry(2024)

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关键词
AXL inhibitor,In vivo antitumor efficacy,6-Naphthyridin-4-one derivatives,Scaffold hopping,Structure-based drug design
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