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Successful Topical Sirolimus Treatment of Epidermal Nevus in a Patient with Phacomatosis Spilosebacea.

Journal of the European Academy of Dermatology and Venereology JEADV(2023)

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Journal of the European Academy of Dermatology and VenereologyEarly View LETTER TO THE EDITOR Successful topical sirolimus treatment of epidermal nevus in a patient with phacomatosis spilosebacea Ana Morelló-Vicente, Ana Morelló-Vicente orcid.org/0000-0001-9342-9698 Department of Dermatology, University Clinic of Navarra, Pamplona, SpainSearch for more papers by this authorInés Oteiza-Rius, Inés Oteiza-Rius orcid.org/0000-0002-5332-4872 Department of Dermatology, University Clinic of Navarra, Pamplona, SpainSearch for more papers by this authorRafael Salido-Vallejo, Corresponding Author Rafael Salido-Vallejo [email protected] orcid.org/0000-0001-7210-8959 Department of Dermatology, University Clinic of Navarra, Pamplona, Spain Correspondence Rafael Salido Vallejo, Department of Dermatology, University Clinic of Navarra, 31008 Pamplona, Spain. Email: [email protected]Search for more papers by this authorJavier Antoñanzas, Javier Antoñanzas orcid.org/0000-0002-8372-5044 Department of Dermatology, University Clinic of Navarra, Pamplona, SpainSearch for more papers by this authorAngela Estenaga, Angela Estenaga Department of Dermatology, University Hospital of Navarra, Pamplona, SpainSearch for more papers by this authorMaider Pretel, Maider Pretel Department of Dermatology, Galdakao-Usansolo Hospital, Vizcaya, SpainSearch for more papers by this authorLeyre Aguado, Leyre Aguado Department of Dermatology, University Clinic of Navarra, Pamplona, SpainSearch for more papers by this author Ana Morelló-Vicente, Ana Morelló-Vicente orcid.org/0000-0001-9342-9698 Department of Dermatology, University Clinic of Navarra, Pamplona, SpainSearch for more papers by this authorInés Oteiza-Rius, Inés Oteiza-Rius orcid.org/0000-0002-5332-4872 Department of Dermatology, University Clinic of Navarra, Pamplona, SpainSearch for more papers by this authorRafael Salido-Vallejo, Corresponding Author Rafael Salido-Vallejo [email protected] orcid.org/0000-0001-7210-8959 Department of Dermatology, University Clinic of Navarra, Pamplona, Spain Correspondence Rafael Salido Vallejo, Department of Dermatology, University Clinic of Navarra, 31008 Pamplona, Spain. Email: [email protected]Search for more papers by this authorJavier Antoñanzas, Javier Antoñanzas orcid.org/0000-0002-8372-5044 Department of Dermatology, University Clinic of Navarra, Pamplona, SpainSearch for more papers by this authorAngela Estenaga, Angela Estenaga Department of Dermatology, University Hospital of Navarra, Pamplona, SpainSearch for more papers by this authorMaider Pretel, Maider Pretel Department of Dermatology, Galdakao-Usansolo Hospital, Vizcaya, SpainSearch for more papers by this authorLeyre Aguado, Leyre Aguado Department of Dermatology, University Clinic of Navarra, Pamplona, SpainSearch for more papers by this author First published: 14 December 2023 https://doi.org/10.1111/jdv.19704Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. REFERENCES 1Asch S, Sugarman JL. Epidermal nevus syndromes: new insights into whorls and swirls. Pediatr Dermatol. 2018; 35(1): 21–29. 10.1111/pde.13273 PubMedWeb of Science®Google Scholar 2Torchia D, Happle R. Phacomatosis spilosebacea: a new name for a distinctive binary genodermatosis. J Am Acad Dermatol. 2023; 89(4): 764–773. 10.1016/j.jaad.2020.12.082 CASPubMedWeb of Science®Google Scholar 3Groesser L, Herschberger E, Sagrera A, Shwayder T, Flux K, Ehmann L, et al. Phacomatosis pigmentokeratotica is caused by a postzygotic HRAS mutation in a multipotent progenitor cell. J Invest Dermatol. 2013; 133: 1998–2003. 10.1038/jid.2013.24 CASPubMedWeb of Science®Google Scholar 4Patel N, Padhiyar J, Patel A, Chhibber A, Patel T, Patel B. Successful amelioration of inflammatory linear verrucous epidermal nevus with topical Sirolimus. Ann Dermatol. 2020; 32(6): 534–536. 10.5021/ad.2020.32.6.534 PubMedWeb of Science®Google Scholar 5Zhou GA, Antaya JA. Topical sirolimus therapy for nevus sebaceus and epidermal nevus: a case series. J Am Acad Dermatol. 2022; 87(2): 407–409. 10.1016/j.jaad.2021.08.029 CASPubMedWeb of Science®Google Scholar 6Salido R, Garnacho-Saucedo G, Cuevas-Asencio I, Ruano J, Galan-Gutierrez M, Vélez A, et al. Sustained clinical effectiveness and favorable safety profile of topical sirolimus for tuberous sclerosis—associated facial angiofibroma. J Eur Acad Dermatol Venereol. 2016; 26: 1315–1318. 10.1111/j.1468-3083.2011.04212.x Google Scholar 7Dodds M, Maguiness S. Topical sirolimus therapy for epidermal nevus with features of acanthosis nigricans. Pediatr Dermatol. 2019; 36(4): 554–555. 10.1111/pde.13833 PubMedWeb of Science®Google Scholar Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation
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Epidermal Nevus Syndromes
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