Sex bias in celiac disease: XWAS and monocyte eQTLs in women identify TMEM187 as a functional candidate gene

Alba Hernangomez-Laderas,Ariadna Cilleros-Portet, Silvia Martínez Velasco,Sergi Marí,María Legarda,Bárbara Paola González-García,Carlos Tutau,Iraia García-Santisteban,Iñaki Irastorza,Nora Fernandez-Jimenez,Jose Ramon Bilbao

Biology of Sex Differences（2023）

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摘要

Celiac disease (CeD) is an immune-mediated disorder that develops in genetically predisposed individuals upon gluten consumption. HLA risk alleles explain 40

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关键词

Celiac disease,XWAS,Mendelian randomization,TMEM187,Monocytes,eQTLs

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