Microsatellite Instability in Gastric Cancer: an Institutional Case Series Analysis in Patients Treated with Neoadjuvant Therapy

Laura Lorenzon,Alberto Biondi,Gloria Santoro,Annamaria Agnes,Antonio Laurino,Antonia Strippoli,Riccardo Ricci,Roberto Persiani,Domenico D'Ugo

Clinical Surgical Oncology（2024）

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摘要

•We investigated a cohort of gastric cancer patients resected after pre-operative treatment for their microsatellite status.•Statistical analyses were computed to correlate the microsatellite instability with clinical and pathological features.•Survivals were analyzed focusing on microsatellite instability and tumor’s regression.•A complete-major response (TRG 1–2) correlated with improved survival.

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关键词

Gastric cancer,Pre-operative treatment,microsatellite instability,MSI,tumor regression grade,Mandard TRG

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