SRSF2 Plays an Unexpected Role As Reader of M5c on Mrna, Linking Epitranscriptomics to Cancer

Hai-Li Ma,Martin Bizet, Christelle Soares Da Costa, Frederic Murisier,Eric James de Bony,Meng-Ke Wang,Akihide Yoshimi,Kuan-Ting Lin,Kristin M. Riching,Xing Wang, John I. Beckman,Shailee Arya,Nathalie Droin,Emilie Calonne,Bouchra Hassabi,Qing-Yang Zhang, Ang Li,Pascale Putmans,Lionel Malbec, Celine Hubert,Jie Lan,Frederique Mies,Ying Yang,Eric Solary,Danette L. Daniels,Yogesh K. Gupta,Rachel Deplus,Omar Abdel-Wahab,Yun-Gui Yang,Francois Fuks

Molecular Cell（2023）

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关键词

RNA modification,SRSF2,SRSF2P95H,NSUN2,m5C,RNA splicing,leukemia,cancer,epitranscriptomics,RNA methylation

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