Malignant degeneration of treated Zenker´s diverticulum

Abstract Text A 75-years-old man with Zenker's diverticulum, endoscopically treated in 2002, presented dysphagia. In the first upper gastrointestinal endoscopy (UGE), a stenosis of benign aspect was observed, suggestive of recurrence of diverticulum. Endoscopic dilation was considered. But, in new UGE, access to the diverticula was achieved, showing a lesion suggestive of infiltrating neoplasm. Histology showed well-differentiated squamous cell carcinoma. Malignant degeneration of Zenker's diverticulum is a rare complication, more than the recurrence of these. Although accessing the diverticulum by endoscopy might be difficult and risky, the diagnosis must be refined before attempting any therapeutic maneuvers. [1]