Exposure to perfluoroalkyl substances and hyperlipidemia among adults: data from NHANES 2017-2018
Journal of Occupational and Environmental Medicine(2023)
摘要
The present study aims to explore the relationship between PFAS exposure and hyperlipidemia using data from NHANES.1600 subjects were included in the analysis, and 9 kinds of PFAS were measured. Multivariate logistic regression analysis was performed to explore the association between serum PFAS and hyperlipidemia.Compared with the lowest quartile of Sm-PFOS, the percentage change for hyperlipidemia was 57% and 41% in the third and highest quartile of PFOS. The positive association between Sm-PFOS and hyperlipidemia remained significant in population aged <60, and the OR for hyperlipidemia in 4th quartile of Sm-PFOS was 1.81.These findings indicated serum Sm-PFOS was independently associated with a higher risk for hyperlipidemia. The epidemiological study warrants further study to elucidate the causal relationship between them.
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关键词
perfluoroalkyl substances,hyperlipidemia
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