Structure of a Human Replisome Shows the Organisation and Interactions of a DNA Replication Machine

Corrigendum16 October 2023free access Structure of a human replisome shows the organisation and interactions of a DNA replication machine Morgan L Jones Morgan L Jones orcid.org/0000-0003-1948-4925 Search for more papers by this author Yasemin Baris Yasemin Baris orcid.org/0000-0003-2791-5588 Search for more papers by this author Martin RG Taylor Martin RG Taylor Search for more papers by this author Joseph TP Yeeles Corresponding Author Joseph TP Yeeles [email protected] orcid.org/0000-0002-2255-2119 Search for more papers by this author Morgan L Jones Morgan L Jones orcid.org/0000-0003-1948-4925 Search for more papers by this author Yasemin Baris Yasemin Baris orcid.org/0000-0003-2791-5588 Search for more papers by this author Martin RG Taylor Martin RG Taylor Search for more papers by this author Joseph TP Yeeles Corresponding Author Joseph TP Yeeles [email protected] orcid.org/0000-0002-2255-2119 Search for more papers by this author Author Information Morgan L Jones, Yasemin Baris, Martin RG Taylor and Joseph TP Yeeles * The EMBO Journal (2023)42:e115685https://doi.org/10.15252/embj.2023115685 This article corrects the following: Structure of a human replisome shows the organisation and interactions of a DNA replication machine25 October 2021 PDFDownload PDF of article text and main figures. ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info The authors contacted the editors after some inaccuracies were identified in the structural coordinates deposited in the PDB. Based on the exchanges between authors and editors, the authors are replacing the PDB model (7PFO) with an updated version and correcting the following figure. PDB deposition (7PFO) is updated in the PDB Figure EV4G is corrected Figure EV4G original. Figure EV4G corrected. Author Statement In the PDB file (PDB:7PFO) that accompanies this manuscript, we have identified several inaccuracies, specifically related to the region of the model comprising the POLE1 subunit of DNA polymerase epsilon and a small region of MCM2. Briefly, the sequence register for a region of POLE1 was shifted during model refinement, a region of the POLE1 homology model used for modelling was adjusted inaccurately, and the register of a helix in MCM2 approaching the MCM2 winged-helix domain is incorrect. Accordingly, to address these matters, the PDB entry has been updated. These updates do not affect the primary conclusions of the manuscript. Expanded View Fig 4, panel G, which describes a small interface between POLE1 and CDC45, has been updated to reflect a change in the revised model. All authors agree with this corrigendum. Previous ArticleNext Article Read MoreAbout the coverClose modalView large imageVolume 42,Issue 22,15 November 2023This cover highlights the article Nix interacts with WIPI2 to induce mitophagy by Eric N. Bunker, Richard J. Youle and colleagues. The minimal essential region of mitophagy receptor Nix recruits WIPI2 to mitochondria for initiation of autophagy upstream of ATG8 proteins. (Cover concept by the authors, scientific illustration by SciStories) Volume 42Issue 2215 November 2023In this issue RelatedDetailsLoading ...