Human Papillomavirus (HPV) Prevalence in Oropharynx Squamous Cell Carcinomas (OPSCC) in Brazil: A Systematic Review with Meta-analysis

Background: Oropharynx squamous cell carcinomas (OPSCC) are an important public health problem. Our study aimed to conduct a systematic review with a metanalysis of the human papillomavirus (HPV) prevalence in OPSCC in Brazil. The aim of our study was to conduct a systematic review with metanalysis about the level of Knowledge of the relation between human papillomavirus (HPV) and OPSCC among university students Methodology: We conducted a systematic review according to the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). We searched MEDLINE/PubMed, SCOPUS, EMBASE and Lilacs for articles published up to March 2023. Results: A total of 260 studies were retrieved with our search strategy, in addition, we included 3 articles manually. After removing duplicate articles, 156 studies remained. Reading the titles and abstracts of these studies, 34 studies were eligible to read the full article. After reading the full text of the selected articles, we excluded 21 articles for reasons such as: no access to the full text (n = 2), literature reviews, systematic reviews, case studies (n = 3), conference proceedings, thesis (n = 6), studies with few participants (n = 2) and studies that did not address the topic (n=8). There were 13 studies left that were included in this systematic review. Conclusion: This study revealed a pooled prevalence of 18% of HPV in OPSCC in Brazil