Supplemental Figure Legend from Therapeutic Challenge with a CDK 4/6 Inhibitor Induces an RB-Dependent SMAC-Mediated Apoptotic Response in Non–Small Cell Lung Cancer

Supplemental Figure 1. RB Regulates RB/E2F Target Gene Transcription and Restricts NSCLC Tumor Burden. Supplemental Figure 2. RB Promotes Cellular Senescence in NSCLC. Supplemental Figure 3. RB Dependent In Vitro Cellular Apoptosis in Response to CDK4/6 Inhibition in NSCLC. Supplemental Figure 4. Mitochondrial Protein SMAC Regulates NSCLC Apoptosis In Vitro. Supplemental Figure 5. Human Transcriptome Array Identifies FOXM1 and Survivin as RB/E2F Signatures. Supplemental Figure 6. RB Mediates Non-small Cell Lung Cancer Apoptosis via RB/IAP/SMAC/Caspase 3 signaling axis.