Three IVIM-DWI Models to Predict Survival Risk in Laryngeal and Hypopharyngeal Squamous Cell Carcinoma Patients after (Chemo)radiotherapy

To investigate the predicted survival risk power of three IVIM-DWI models in laryngeal and hypopharyngeal squamous cell carcinoma (LHSCC) patients after (chemo)radiotherapy, 45 patients were retrospectively enrolled. IVIM-DWI sequence scanning was performed using echo planner imaging (EPI) sequence with 12 b values (0, 10, 20, 30, 50, 70, 100, 150, 200, 400, 800 and 1000 s/mm2). Followed up for 2-72 months with median follow-up of 14 months. The pretreatment ADC, D, f value and D* value were significantly correlated with prognosis of local disease, and the pretreatment ADC, D* value were independent biomarkers for survival risk prediction.