Supplementary Figures 1 - 6 from A Cross-Species Analysis in Pancreatic Neuroendocrine Tumors Reveals Molecular Subtypes with Distinctive Clinical, Metastatic, Developmental, and Metabolic Characteristics

Supplementary Figure 1. NMF analysis of PanNET miR expression and its validation. Supplementary Figure 2. NMF analysis of PanNET gene expression and its validation. Supplementary Figure 3. Cross-species analysis of gene expression subtypes in human and mouse PanNETs. Supplementary Figure 4. ENPP2 and INS mRNA expression in human PanNET subtypes as assessed using human PanNET core clinical gene expression microarray dataset. Supplementary Figure 5. Comparison of mouse PanNET subtypes to microdissected invasive IT vs. non-invasive IC2 of mouse PanNET tumors: Relationship to PanNET histotypes and progenitor gene signatures. Supplementary Figure 6. Metabolic profiles of IT and MLP cell lines.