Figure S3 from Imaging of Cancer Γ-Secretase Activity Using an Inhibitor-Based PET Probe

Supplementary Figure 3. Representative PET imaging of endogenously developed mammary tumors from MMTVPyMT transgenic mice using [124I]PN67. The tumor location was indicated by red cycles. PET imaging studies were performed at 2h post-injection on a microPET scanner with (bottom panel) or without (top panel) blocking inhibitor (1, 30mg/kg).