Free Radical Based Nano Cancer Therapy

Free radicals were formerly considered as a highly reactive, transient, and destructive entities. Free radicals are exceedingly unstable and highly reactive with other biological molecules, often having one or more unpaired electrons. Free radicals' open-shell electrical structure makes them ready for harnessing in biological applications. In particular, free radical regulation-based nanotherapeutics have become a novel therapy option for cancer. Recent developments on free radicals and their uses in cancer therapy are discussed in this review. Photodynamic treatment (PDT), sonodynamic therapy (SDT), radiation therapy (RT), chemodynamic therapy (CDT), and ferroptosis therapy are only some of the emerging approaches that rely on the creation of free radicals by nanoparticles (NPs) which discussed here. Finally, several challenges and promising future directions for free radical regulation-based nanotherapeutics in cancer therapy are highlighted.