PHOTOBIOMODULATION OF CHONDROCYTES: GLOBINCOUPLED SIGNAL NETWORK

The comparison between the photobiomodulation (laser, 670 or 1560nm) of collagen synthe-sis by chondrocytes revealed the participation of cytoglobin in the reception of laser signal. It is assumed that signal network has been triggered via laser induced coupling of cytoglobin with 2-oxoglutarate-dependent dioxygenases: prolyl hydroxylase domain of HIF, histone demethylases and prolyl-hydroxylase of collagen.