Convenient multicomponent synthesis of furo[3,2-c]coumarins in the promoting medium DIPEAc and assessment of their therapeutic potential through in silico pharmacophore based target screening

A one-pot three-component approach for the synthesis of dihydrofuro[3,2- c ]coumarins was developed via the reaction of aryl/hetryl aldehydes, substituted phenacyl bromides and 4-hydroxycoumarin using N , N -diisopropyl ethyl ammonium acetate as the promoting medium.