P.187 Variability of schizophrenia-associated genetic variants across the populations

European Neuropsychopharmacology(2020)

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摘要
An anionic Zn(II) Metal-Organic Framework, [HDMA]2[Zn2(BDC)3(DMA)2].6DMF (HDMA+: dimethylamonnium, BDC2−: 1,4-benzenedicarboxilate, DMA: dimethylamine, DMF: N,N′-dimethylformamide), was served as a host for encapsulating I2. For comparison of the ad/desorption rates of iodide, the ion exchange process with organic cations have been done. Loading of the exchanged compounds were successfully done by suspending them in a solution of I2 in cyclohexane. Powder X-ray diffraction experiments and IR analysis showed that the exchanged crystalline lattices after adsorption and desorption of iodide remained the same. The delivery of I2 from the compounds performed in ethanol, were determined by UV/vis spectroscopy. Comparison of iodide adsorption and desorption rates in the exchanged compounds showed that presence of different organic cations have effective role in increasing iodine adsorption.
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关键词
genetic variants,variability,schizophrenia-associated
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