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Effectiveness of L-serine Supplementation in Children with a GRIN2B Loss-of-function Mutation: Rationale and Protocol for Single Patient (N-of-1) Multiple Cross-over Trials

Bibiche den Hollander, Marieke Rothuizen-Lindenschot,Lisa Geertjens,Frederic M. Vaz,Marion M. Brands,Hoang Lan Le,Agnies M. van Eeghen,Peter M. van de Ven,Martina C. Cornel,Bart A. W. Jacobs,Hilgo Bruining,Clara D. van Karnebeek

CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS（2023）

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Key words
GRIN2B1,L-serine2,Intellectual developmental disability3,N-methyl-D-aspartate receptor4,Personalized medicine5,n-of-16
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