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Design, Synthesis, and Biological Characterization of Proteolysis Targeting Chimera (protacs) for the Ataxia Telangiectasia and RAD3-related (ATR) Kinase

Abdallah M. Alfayomy,Ramy Ashry,Anita G. Kansy, Anne-Christin Sarnow,Frank Erdmann,Matthias Schmidt,Oliver H. Kraemer,Wolfgang Sippl

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY（2024）

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关键词
Ataxia telangiectasia and RAD3-Related (ATR) kinase,Proteolysis targeting chimera (PROTAC),Protein degradation,Synthesis,MIA PaCa-2
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