First-Trimester Maternal Hemodynamics in Patients with or Without Chronic Hypertension Using USCOM (ultrasound Cardiac Output Monitor), A Non-invasive and Quantitative Method

Objective: We aim to investigate maternal hemodynamics at 10-14 weeks of gestation among patients with and without chronic hypertension, utilizing USCOM®, a non-invasive cardiac output monitor. Methods: A prospective pilot study was conducted for women with singleton pregnancies. Independent T, Mann-Whitney U, and Chi-square tests were used to analyze cardiovascular parameters via Doppler waveform. Results: Thirteen pregnant women with preexisting hypertension and no other medical comorbidities were selected, and 26 controls were matched based on maternal age, ethnicity, and BMI in a ratio of 1:2. Six patients with chronic hypertension were on anti-hypertensive medications. Tables 1 and 2 present each respective group's basic demographic and hemodynamic characteristics. Conclusion: Despite no differences in BP, our study revealed significant hemodynamic changes in chronic hypertensive patients in the first trimester. Chronic hypertensive patients might have pre-existing pathological cardiovascular adaptation in early pregnancy, potentially compromising perinatal outcomes.