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Supplementary Methods, Table 1 from A Phase I/II, Multiple-Dose, Dose-Escalation Study of Siltuximab, an Anti-Interleukin-6 Monoclonal Antibody, in Patients with Advanced Solid Tumors

Eric Angevin, Josep Tabernero,Elena Élez, Steven J. Cohen,Rastilav Bahleda,Jean‐Luc Van Laethem, Christian H. Ottensmeier,José A. López-Martín,Sally Clive, Florence Joly, Isabelle Ray‐Coquard, Luc Dirix, Jean‐Pascal Machiels,Neil Steven,Manjula Reddy, Brett M. Hall,Thomas A. Puchalski,Rajesh Bandekar, Helgi van de Velde, Brenda Tromp,Jessica Vermeulen, Razelle Kurzrock

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摘要
PDF file - 99KB, Supplementary Methods: The supplemental material contains additional detail on the pharmacokinetic and pharmacodynamic methods used during the study as well as a summary table of safety events and a figure detailing patient disposition. Supplemental Table 1: Summary of safety events in all study cohorts.
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Combination Therapies
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