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Mistranslation-associated Perturbations of Proteostasis Do Not Promote Accumulation of Amyloid Beta and Plaque Deposition in Aged Mouse Brain

Harshitha Santhosh Kumar,James Moore,Adrian C. Steiner, Emmanuel Sotirakis, Benjamin Schärli,Patricia Isnard-Petit,Kader Thiam,David P. Wolfer,Erik C. Böttger

CELLULAR AND MOLECULAR LIFE SCIENCES（2023）

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Key words
Proteostasis,Neurodegenerative disease,Alzheimer’s disease,Error-prone translation,Protein misfolding,Amyloid beta
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