The inferior performance of [ 68 Ga]Ga-FAPI-04 PET/CT as a diagnostic and theranostic biomarker in [ 177 Lu]Lu-DOTATATE refractory well-differentiated neuroendocrine tumors.

Duygu Has Simsek,Yunus Guzel,Dilara Denizmen,Yasemin Sanli,Fikret Buyukkaya,Bilal Kovan,Halil Komek,Emine Goknur Isik,Zeynep Gozde Ozkan,Serkan Kuyumcu

European journal of nuclear medicine and molecular imaging（2023）

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摘要

Our preliminary results demonstrated that [Ga]Ga-FAPI-04 PET/CT mainly failed in well-differentiated NETs refractory to [Lu]Lu-DOTATATE therapy and had a limited role as an alternative diagnostic or theranostic agent. Further investigations with a larger patient population are required to determine the impact of [Ga]Ga-FAPI-04 PET/CT on NETs.

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