Improved Sexual Function after Parathyroidectomy in Women with Primary Hyperparathyroidism.

Background: The study aimed to evaluate whether women with primary hyperparathyroidism (PHPT) experience improvement in their sexual function after parathyroidectomy. Methods: Women with PHPT or benign thyroid nodules (controls) undergoing surgery were administered the validated Parathyroidectomy Assessment Score (PAS), Patient-Reported Outcomes Measurement Information System-29 (PROMIS-29) and Female Sexual Function Index (FSFI) pre-operatively, at 3 months and 6 months postoperatively. Results: Of the 26 PHPT and 18 control patients, PHPT patients were older (53.1 vs 45.3 years, p = 0.008). Postoperatively, both PHPT (pre-op 2.4 vs 3-month 3.0 vs 6-month 2.4, p = 0.022) and control patients (pre-operative 2.4 vs 3-month 3.3 vs 6-month 3.6, p = 0.032) reported increased desire for sexual activities. In addition, PHPT patients experienced increased arousal (pre-operative 2.7 vs 3-month 3.9 vs 6-month 3.6, p = 0.047) and satisfaction (pre-operative 3.0 vs 3-month 4.8 vs 6-month 4.0, p = 0.006). Conclusions: The current study indicates that women with PHPT may experience improved sexual function after parathyroidectomy.