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Detection of Plasma, Platelets, Hemoglobin in Blood Sample of Dengue Malaria Based on Surface Plasmon Resonance Biosensor Using Black Phosphorus: A Numerical Analysis

PLASMONICS(2024)

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摘要
The present work focuses on the detection of dengue virus using a proposed copper (Cu) and black phosphorus (BP)–based SPR sensor. This proposed sensor is capable of detecting normal and infected blood samples containing plasma, platelets and hemoglobin. We studied the performance parameter at optimized Cu layer thickness of the proposed sensor by calculating that the maximum sensitivity is 150.55°/RIU, 226.73°/RIU and 295.58°/RIU at Rmin values with 57 nm, 57 nm and 51 nm thickness of Cu layer for the detection of plasma, platelet and hemoglobin in the blood sample of dengue malaria. The properties of BP combined with the unique plasmonic properties of SPR sensors can result in enhanced interactions between surface plasmons and incident light. These results are intended for improved sensitivity and remarkable figure of merit (FoM). We also calculated the electric field and penetration depth (PD) for the same sample. In this study, the normal and infected blood samples are successfully examined for the performance parameters for the plasma, platelets and hemoglobin.
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关键词
Surface plasmon resonance,Sensitivity,Electric field intensity,Penetration depth
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