CC chemokines Modulate Immune responses in Pulmonary Hypertension

•The immune response and inflammation in pulmonary hypertension (PH) have been systematically summarized based on recent studies.•The relationship between CC chemokines and the pathogenesis of pH is summarized in clinical and animal models.•We found that although the immune response serves as an important potential factor in the pathogenesis of PH, less attention has been paid to CC chemokines and their receptors.•We believe that a greater understanding of the relationship between PH and CC chemokines and their receptors is a pressing issue.•We believe that we need to further clarify the pathogenesis of pH and provide basis for the clinical treatment of PH.