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Design, Synthesis and Preclinical Evaluation of Muscarine Receptor Antagonists Via a Scaffold-Hopping Approach

Marlon Millard,Jonas Kilian,Marius Ozenil, Mariella Mogeritsch, Verena Schwingenschloegl-Maisetschlaeger,Wolfgang Holzer,Marcus Hacker,Thierry Langer,Verena Pichler

European Journal of Medicinal Chemistry(2023)

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关键词
Muscarinic acetylcholine receptors,Pirenzepine,Orthosteric binding site
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