Evaluation of Genetic Mutations Associated with Phenotypic Resistance to Fluoroquinolones, Bedaquiline, and Linezolid in Clinical Mycobacterium Tuberculosis: A Systematic Review and Meta-Analysis

Qi An,Rui Lin,Qing Yang,Chuan Wang,Dongmei Wang

Journal of Global Antimicrobial Resistance（2023）

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摘要

•Drug susceptibility testing is required to optimize Group A drug use for MDR-TB.•Mutations were correlated with phenotypic resistance to LFX and MFX.•Mutation-phenotype associations for BDQ and LZD were absent.

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关键词

Mycobacterium tuberculosis,Fluoroquinolones,Bedaquiline,Linezolid,Mutations,Resistance

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