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2249P Mitigation of tumor microenvironment-mediated immunosuppression using a PD1-41BB switch protein with optimal affinity tcrs for first-in-class, 3rd generation TCR-T therapies

K. Crame, G. Longinotti, M. Catarinella, P. Prinz, S. Tippmer,K. Mutze, A. Coluccio,M. Salvermoser, J. Bittmann, M. Bürdek, B. Lösch, C. Geiger, K. Davari,D.J. Schendel

Annals of Oncology（2023）

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关键词
immunosuppression,microenvironment-mediated,first-in-class
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