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Association of Body Mass Index with Risk of Cardiometabolic Disease, Multimorbidity and Mortality: a Multi-State Analysis Based on the Kailuan Cohort.

ENDOCRINE(2024)

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摘要
To evaluate the association of body mass index (BMI) with risk of first cardiometabolic disease (FCMD), cardiometabolic multimorbidity (CMM) and death. 87,512 participants free of CMD were included from the Kailuan cohort, which was established during 2006–2007 and followed up until 2020. BMI was classified as underweight ( < 18.5 kg/m2), healthy weight (18.5–23.9 kg/m2), overweight (24.0–27.9 kg/m2), mildly obese (28.0–31.9 kg/m2), and severely obese ( ≥ 32.0 kg/m2). FCMD was defined as the first onset of diabetes, heart disease, or stroke, and CMM as the coexistence of at least two CMD. The hazard ratio (HR) and 95
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关键词
Body mass index,Cardiometabolic disease,Cardiometabolic multimorbidity,Multi-state model,Prospective cohort study
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