Study Protocol for a Multicenter Randomized Controlled Pilot Study on Decompressive Laparotomy Vs. Decompressive Craniectomy for Intractable Intracranial Pressure after Traumatic Brain Injury: the SCALPEL Study

Benny Kölbel,Alexander Novotny,Arnulf Willms,Victoria Kehl,Bernhard Meyer,Uwe-Max Mauer,Sandro M. Krieg

Brain and spine（2023）

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摘要

•Novel approach to lower intracranial pressure after traumatic brain injury.•1:1 randomization of decompressive laparotomy vs. hemicraniectomy.•Decompressive laparotomy is supposed to increase venous outflow.•Non-inferiority design, pilot study.•Primary outcome is Glasgow Outcome Scale Extended.

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关键词

Traumatic brain injury,Intracranial pressure,Decompressive craniectomy,Decompressive laparotomy

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